Adult: SC Prophylaxis of venous thromboembolism during surgery Low-moderate risk: 20 mg once daily, start 2 hr before start of procedure. High risk: 40 mg once daily, start 12 hr before start of procedure. For hip replacement surgery: 40 mg once daily for a further 3 wk. For immobilised patients: 40 mg once daily for at least 6 days or until patient is ambulant, up to a max of 14 days. Deep vein thrombosis 1 mg/kg 12 hrly for 5 days and until oral anticoagulation is established. Prevention of clotting in extracorporeal circulation during haemodialysis 1 mg/kg into the arterial line of the circuit at the start of the dialysis session. Give a further dose of 0.5-1 mg/kg if needed. Unstable angina 1 mg/kg 12 hrly for 2-8 days w/ low dose .
2What are the Side Effects ?
Thrombocytopenia, mild bleeding, inj site irritation, pain and ecchymoses, hypersensitivity and erythema. Potentially Fatal: Haemorrhagic complications.
3What Precautions should be taken ?
Renal or hepatic impairment, history of GI ulceration, uncontrolled hypertension, spinal or epidural anaesthesia; lactation and pregnancy; elderly. Periodic blood counts, platelet count and stool occult blood test recommended.
4Do not take this if you have any of the below ...